In Slovenia, the breeding of indigenous domestic animals is becoming less attractive, and out of 15 indigenous breed 14 are endangered. The Carniolan honey bee being the only exception. Eleven out of 13 traditional breeds are also endangered. The share of introduced animal breeds and cross-breeds with introduced breeds has been increasing. The breeds and races where the adaptation to natural conditions is the strongest are the most successful with defying the introduced breeds.

Life expectancy at birth in Slovenia is gradually increasing for both men and women. It is slightly higher for women than for men. Longer life expectancy at birth is recorded in western Slovenia. In 2021, life expectancy at birth was 83.8 years for women and 77.7 years for men, with an average of 80.7 years in Slovenia compared to 80.1 years in the EU.

As of 2022, the Potentially Contaminated Sites (PCS) inventory in Slovenia includes 671 sites that are a potential source of pollution due to past or present activities. With the establishment of the first database, Slovenia has taken the first of six steps toward systematic management and monitoring of contaminated sites. An analysis of the degree of environmental sensitivity and threat to human health due to potential contamination revealed that priority treatment is urgent for 35 sites and very urgent for 196 sites.

In the period 1992–2022 the consumption of mineral fertilizers in Slovenia was reduced by 38%. In the same period the consumption of plant nutrients (N, P₂O₅, K₂O) per hectare of utilized agricultural area also reduced by 30%. The average consumption per hectare of utilized agricultural area was 61 kg N, 25 kg P₂O₅ and 31 kg K₂O. In the period 2012–2019 the average consumption of nitrogen in Slovenia was lower (57 kg N/ha) than in EU member states (63 kg N/ha).

Foodborne diseases remain an important public health challenge and they are an important cause of morbidity and mortality worldwide. During 2018–2022 Slovenia reported 1152 different outbreaks. The most common were the respiratory disease outbreaks (902), outbreaks with contact transmission (186), followed by and foodborne disease outbreaks (22).